2018-03-13 04:58:05 UTC
or on public forums. While Neo Darwinism claims that mutation
is a source of new information and natural selection becomes involved
in the evolution of organisms, there is proofreading and repair which is
designed to detect faulty new DNA and begin operations to correct the
errors by removing and replacing the faulty DNA.
Possibly the reason this topic is not so commonly discussed is because
the origin of this process of proofreading and repair is difficult to
By what procedure could mutation create the proofreading and repair.
No one that I've read provides any details as to how, by what means
and what steps could this have come about.
To provide the standard
line of mutation and natural selection explains nothing where
error in copying occurs.
From article on DNA proofreading and repair:
"DNA replication is a highly accurate process, but mistakes can
occasionally occur as when a DNA polymerase inserts a wrong base.
Uncorrected mistakes may sometimes lead to serious consequences, such as
cancer. Repair mechanisms can correct the mistakes, but in rare cases
mistakes are not corrected, leading to mutations; in other cases, repair
enzymes are themselves mutated or defective.
Mutations: In this interactive, you can “edit” a DNA strand and cause a
mutation. Take a look at the effects!
Most of the mistakes during DNA replication are promptly corrected by
DNA polymerase which proofreads the base that has just been added. In
proofreading, the DNA pol reads the newly-added base before adding the
next one so a correction can be made.
The polymerase checks whether the newly-added base has paired correctly
with the base in the template strand. If it is the correct base, the
next nucleotide is added. If an incorrect base has been added, the
enzyme makes a cut at the phosphodiester bond and releases the incorrect
nucleotide. This is performed by the exonuclease action of DNA pol III.
Once the incorrect nucleotide has been removed, a new one will be added
It seems clear that this is design.